VEGFR2/CD309 anticorps (Soluble)

N° du produit ABIN1589863

Cet anticorps Lapin Polyclonal détecte spécifiquement VEGFR2/CD309 dans WB. Il présente une réactivité envers Souris.

Aperçu rapide pour VEGFR2/CD309 anticorps (Soluble) (ABIN1589863)

Antigène: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VEGFR2/CD309 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-VEGFR2/CD309 anticorps

Épitope: Soluble

Fonction: VEGFR-2/Flk-1 (Peptide), soluble antibody

Specificité: Peptide: GMEASLGDRIAMP

Attributs du produit: Chromosomal location: 5 C3.3, 5 42.0 cM
Produced from sera of rabbits immunised with a peptide of the C-terminal end of native mouse soluble VEGFR-2/Flk-1 (GMEASLGDRIAMP).

Purification: Anti-human soluble VEGFR-2/KDR was purified by affinity chromatography with immobilized Protein A.

Immunogène: Peptide: GMEASLGDRIAMP

Isotype: IgG

Information d'application

Indications d'application: Western Blot: use at 1-5 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Conseil sur la manipulation: Centrifuge vial prior to opening.

Stock: 4 °C,-20 °C

Stockage commentaire: The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

Date de péremption: 24 months

Détails sur VEGFR2/CD309

Antigène: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Autre désignation: VEGFR-2/Flk-1

Sujet: Soluble vascular endothelial growth factor receptor-2 , soluble Kdr, soluble Ly73, soluble Flk-1, sVEGFR2, sVEGF receptor 2, soluble kinase insert domain protein receptor,The antibody recognizes solely the endogenous soluble form of mouse vascular endothelial growth factor receptor 2, alos known as CD309, VEGFR2, KDR, protein tyrosine kinase receptor flk-1, and fetal liver kinase-1. The endogenous soluble mouse esFlk-1 generated by alternative splicing consists of the first 6 Ig-like loops followed by the unique C-terminal end: GMEASLGDRIAMP. Flk-1 is a member of the tyrosine protein kinase family, sub-family CSF-1/PDGF, that contains a single pass transmembrane receptor with a protein kinase domain and seven immunoglobulin-like domains in the extracellular region. Flk-1 is expressed at high levels in adult heart, lung, kidney, brain, and skeletal muscle, other tissues express at lower levels. Flk-1 is a receptor for VEGF-A or fully processed VEGF-C, ligand binding plays a key role in vascular development and vascular permeability.

ID gène: 16542

UniProt: P35918

Pathways: Signalisation RTK, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling